Programação
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Engenharia genética para produção de células tronco universais
Palestrante: Prof. Dr. Ernesto Goulart
Cientista e empreendedor. Doutor e mestre em Genética pela Universidade de São Paulo e UFJF/Temple University. Expert em engenharia genética utilizando o sistema CRISPR-Cas9, xenotransplante, células tronco, medicina regenerativa e engenharia de tecidos (e.g. bioimpressão 3D, organóides, descelularização de órgãos, etc). Membro premiado da International Society for Stem Cell Research (ISSCR) e International Society for Cell and Gene Therapy (ISCT). Primeiro autor de diversos trabalhos científicos em revistas de alto impacto (e.g. Nature Communications, Biofabrication, Cancer Research, etc). Especialista em desenvolvimento de negócios e empreendedorismo científico. Co-fundador de startups em biotecnologia. Conselheiro e assessor científico.
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3D architecture of chromatin and other epigenetic mechanisms implicated in normal and pathological development
Palestrante: Prof. Dr. Veniamin Fishman
Talk summary: The talk covers topics related to epigenetic regulation of gene expression, with a particular focus on genome architecture (chromatin compartments, TADs, loops) and its alterations caused by chromosomal rearrangements. There will be an overview of the chromatin conformation capture methods devoted to studying genome organization: Hi-C and others. We will discuss the main mechanisms underlying chromatin packaging and how these mechanisms can be implicated in human congenital diseases. How Hi-C-based methods can be used for genome assembly and identification of point mutations and chromosomal rearrangements in human genome. Finally, we discuss recent ML-based computational algorithms predicting changes in chromatin architecture, epigenetic states, and gene expression and their applications to study variants of unknown significance.
Dr. Fishman is a Group leader (PI) at the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences.
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The PUMAS Project: A step towards global representation in psychiatric genetics
Palestrante: Prof. Nelson Freimer MD PhD
Nelson B. Freimer, MD is the Maggie G. Gilbert Endowed Chair and Distinguished Professor of Psychiatry and Human Genetics at UCLA. He is the Founding Director of UCLA’s Center for Neurobehavioral Genetics and of the UCLA Neuroscience Genomics Core. Dr. Freimer’s research focuses on the use of novel strategies for behavioral phenotyping and large-scale genomics methods to identify the genetic basis of complex traits, including such neurobehavioral disorders as bipolar disorder, schizophrenia, and depression. He also leads UCLA’s Depression Grand Challenge (DGC), a university-wide initiative that aims to transform our understanding and treatment of depression and thereby cut the burden that it represents to health and well-being in half by the year 2050. Within the DGC he is the PI of the UCLA-Apple Digital Mental Health Study.
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A história evolutiva das baleias contada pelos genes
Palestrante: Prof. Dra. Mariana Freitas Nery
Quando? Segunda-feira, 08/05 às 13h
Onde? Sala Therezinha Ungaretti (Sala 201), Dep. de Genética e Biologia Evolutiva | IB-USP
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Assinaturas de processos microevolutivos em árvores filogenéticas
Palestrante: Prof. Dra. Flavia Maria Darcie Marquitti
Quando: 15/05
Sala Therezinha Ungaretti
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Uso de células-tronco pluripotentes induzidas como modelo in vitro para o estudo da neurobiologia da síndrome de Down
Palestrante: Dra. Bruna Lancia Zampieri
Ciclo 2023.1 de Seminários do Departamento de Genética e Biologia Evolutiva do Instituto de Biociências USP. Temos a honra de convidá-los a assistir à palestra abaixo.
Quando? Segunda-feira, 29/05/2023 às 13h
Onde? Sala Therezinha Ungaretti (Sala 201), Depto de Genética e Biologia Evolutiva, IB-USPRua do Matão, 277 CEP 05508090
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