Programação

  • General Information & News

    The first in-person meeting will be on 31 March 2023

    Look up for me in my office at 2 pm

  • LGN0341 - Cytogenomics and Epigenetics

    Program


    • 17/03/2023 - Class 1 - Introduction to Cytogenomics and Epigenetics
    • 24/03/2023 - Class 2 - Module-1: Cell Cycle, Mitosis and Meiosis | Seminar Presentation
    • 31/03/2023 - Class 3 - Module-1: Cell Cycle, Mitosis and Meiosis | Seminar Presentation
    • 07/04/2023 - No class - Easter
    • 14/04/2023 - Class 4 - Module-2: Chromatin and Chromosomes | Seminar Presentation
    • 21/04/2023 - No class - Tiradentes
    • 28/04/2023 - Class 5 - Module-2: Chromatin and Chromosomes | Seminar Presentation
    • 05/05/2023 - Class 6 - Module-3: Genome Organisation | Seminar Presentation
    • 12/05/2023 - Class 7 - Module-3: Genome Organisation | Seminar Presentation
    • 19/05/2023 - No class - Brazilian Meeting of Cytogenetics and Cytogenomics
    • 26/05/2023 - Class 8 - Module-4: Aneuploidy and Polyploidy | Seminar Presentation
    • 02/06/2023 - Class 9 - Module-4: Aneuploidy and Polyploidy | Seminar Presentation
    • 09/06/2023 - No class - Corpus Christi
    • 16/06/2023 - Class 10 - Module-5: Structural Chromosome Changes | Seminar Presentation
    • 23/06/2023 - Class 11 - Module-5: Structural Chromosome Changes | Seminar Presentation
    • 30/06/2023 - Class 12 - Module-6: Epigenetics and Epigenetic Inheritance | Seminar Presentation
    • 07/07/2023 - Class 13 - Module-6: Epigenetics and Epigenetic Inheritance | Seminar Presentation
    • 14/07/2023 - Class 14 - Final Presentation


    Concept map

    A concept map must be created for every lesson based on the readings and studies. The concept map is delivered during the next class. It is not accepted delays.


    Seminars

    A seminar must be prepared and presented for every lesson in the next week after theoretical class. The seminar can not be shorter than 20 minutes and it must cover the specific topic completely. The professor should request to present only a subtopic or reorganize presentations to create the dynamic and understanding needed to give flow to the content.


    Monograph

    A bibliographic review should be written in standard English and must follow the manuscript instruction of a high-quality scientific journal. The theme should be discussed with the Professor for a joint decision. The manuscript should be deposited according to the program as a PDF file, direct to Professor’s e-mail. The scientific journal chooses to follow the instruction must be informed to the professor in advance. The bibliographic review may contemplate any subject presented in the context of the discipline and personal interests are strongly encouraged. The bibliographic revision must be made based on scientific papers of a high-quality journals with the complete editorial process only.


    Final Exam and Passport

    There is only one final exam. Students can ear passport making and delivering all seminar presentations, concept maps and monograph over the average. For those who will fulfill these requirements, the passport will be given for final exam dispensation.


    Final Grade

    The final grade is calculated by the average of the final exam score with a weigh of 7 and the monograph score with a weigh of 3. If the student got a passport, his/her final grade will be calculated by 5.0 plus the monograph score (exceptionally in this case varying from 0 to 5)


  • Introduction

    Introduction to Cytogenomics and Epigenetics


    Chapter 1 - Introduction to the Study of Chromosomes. pp. 3-6.
    Chapter 2 - A Historical Perspective on Chromosome Structure, Function, and Behavior. pp. 7-21.





  • Module -1 - Cell Cycle, Mitosis and Meiosis

    Part 1 - Cell Cycle and Mitosis



    Chapter 4 - Chromosomes in the Mitotic Cell Cycle. pp. 33 - 43





    Part 2 - Meiosis

     Chapter 5 - Meiosis and Gamete Formation: A view of Chromosomes in the Germline. pp. 44-66

    Part 3 - Gametogenesis




    Chapter 19 - Introduction to the Angiosperms. pp. 465 - 476


  • Module - 2 - Chromatin and Chromosomes

    Part 1 - Chromatin and Chromosomes

     Chapter 4 - DNA, Chromosomes, and Genomes

    DNA molecules are highly condensed in chromosomes. pp. 210.

    Nucleosomes are a basic unit of eukaryotic chromosome structure. pp. 211.

    The structure of the nucleosome core particle reveals how DNA is packaged. pp. 212.

     Nucleosomes are usually packed together into a compact chromatin fiber. pp. 216.

    Mitotic chromosomes are formed from chromatin in its most condensed state. pp. 243.


    Part 2 - Chromosomal Landmarks




    Chapter 20 - Molecular Analysis of Chromosomal Landmarks. pp. 296-317


  • Module - 3 - Genome Organisation

    Part 1 - Genome Size and Tandem Repetitive Sequences

     


    Subchapter 7.2 - The Genetic Features of Eukaryotic Nuclear Genomes. pp. 203 - 219





    Part 2 - Dispersed Repetitive Sequences

     Chapter 9 - Virus Genomes and Mobile Genetic Elements. pp. 249 - 263



  • Module - 4 - Aneuploidy and Polyploidy

    Part 1 - Aneuploidy



    Chapter 11 - Deviations from Basic Chromosome Numbers - Aneuploidy. pp. 160-174





    Part 2 - Polyploidy



    Chapter 10 - Multiples of Basic Chromosome Numbers - Polyploidy. pp. 139-159

    Chapter 12 - The Cytogenetic Analysis of Haploids. pp. 175-185




  • Module - 5 - Structural Chromosome Changes

    Part 1 - Introduction to Chromosome Rearrangements. Deficiences and Duplications



    Chapter 7 - Structural Stability of Chromosomes. pp. 87 - 102.

    Chapter 8 - Losses and Gains of Chromosome Segments. pp. 103 - 113.




    Part 2 - Inversions and Translocations



    Chapter 9 - Rearrangements of Chromosome Segments. pp. 115 - 136.





  • Module - 6 - Epigenetics

    Part 1 - Introduction to Epigenetics & Epigenetic Information


    Capítulo 1 - Epigenética - Histórico e Conceitos. pp. 15 - 23.

    Capítulo 2 - Modificações Epigenéticas I. Conformação da Cromatina e Modificação do DNA. pp. 25 - 42.


    Part 2 - Epigenetic Information & Examples


    Capítulo 3 - Modificações Epigenéticas II. Modificações pós-traducionais de histonas. pp. 43 - 65.

    Capítulo 4 - Modificações Epigenéticas III. RNAs não Codificadores (ncRNA). pp. 67 - 97.

    Capítulo 6 - Impressão Genômica. pp. 131 - 154.


  • References

  • Concept Map - Examples