# Biossíntese de PHAmcl a partir de glicose considerando também a biossíntese de biomassa 
# considera vias ED (ciclica ou não), PPP, CK, Glioxilato, anapleróticas, transidrogenase e respiração aeróbia de coenzimas 
# 10000 XR igual a 1.000.000 g de XR ou 1 XR igual a 100 g
#
# 2017: removed VP5, put ATP and ADP as internal metabolites
#
-ENZREV
EMP2 EMP4 EMP5 EMP6 EMP7 EMP8 EMP9 VP6 VP7 VP8 VP9 VP10 TRANS 

-ENZIRREV
EMP1 ED1 ED2 EMP10 CPD VP1 VP5 CK1 CK2 CK3 CK4 CK5 CK6 CK7 CK8 CGLX1 CGLX2 GLN3 AD1 AD2 P3HHx P3HO P3HD P3HDd BIOMASSA OXFAD OXNAD 

-METINT
G6P KDPG2 NADP NADPH PG6 PIR G3P BPG13 PG3 PG2 PEP AcCoA Rbl5P Rb5P X5P S7P E4P F6P DHP F16P OAA Cit KG2 IsoCit SucCoA Suc Fum Mal GLX FAD FADH2 NAD NADH CoASH 

-METEXT
Gliex CO2 O XR HHx HO HD HDd ADP ATP

-CAT
EMP1 : Gliex + ATP = G6P + ADP .
EMP2 : G6P = F6P .
ED1 : PG6 = KDPG2 .
ED2 : KDPG2 = PIR + G3P .
EMP4 : F16P = G3P + DHP .
EMP5 : DHP = G3P .
EMP6 : G3P + NAD = BPG13 + NADH .
EMP7 : BPG13 + ADP = PG3 + ATP .
EMP8 : PG3 = PG2 .
EMP9 : PG2 = PEP .
EMP10 : PEP + ADP = PIR + ATP .
CPD : PIR + NAD + CoASH = AcCoA + NADH + CO2 .
VP1 : G6P + NADP = PG6 + NADPH .
VP5 : PG6 + NADP = NADPH + Rbl5P + CO2 .
VP6 : Rbl5P = Rb5P .
VP7 : Rbl5P = X5P .
VP8 : Rb5P + X5P = S7P + G3P .
VP9 : G3P + S7P = E4P + F6P .
VP10 : X5P + E4P = F6P + G3P .
CK1 : OAA + AcCoA = Cit + CoASH .
CK2 : Cit = IsoCit .
CK3 : IsoCit + NADP = KG2 + NADPH + CO2 .
CK4 : KG2 + NAD + CoASH = SucCoA + NADH + CO2 .
CK5 : SucCoA + ADP = Suc + ATP + CoASH .
CK6 : Suc + FAD = Fum + FADH2 .
CK7 : Fum = Mal .
CK8 : Mal + NAD = OAA + NADH .
CGLX1 : IsoCit = GLX + Suc .
CGLX2 : GLX + AcCoA = Mal + CoASH .
GLN3 : F16P = F6P .
AD1 : PIR + CO2 + ATP = OAA + ADP .
AD2 : OAA + ATP = PEP + ADP + CO2 .
P3HHx : 3 AcCoA + 3 NADPH + 2 ATP = HHx + 3 CoASH + 3 NADP + 2 ADP .
P3HO : 4 AcCoA + 5 NADPH + 3 ATP = HO + 4 CoASH + 5 NADP + 3 ADP .
P3HD : 5 AcCoA + 7 NADPH + 4 ATP = HD + 5 CoASH + 7 NADP + 4 ADP .
P3HDd : 6 AcCoA + 9 NADPH + 5 ATP = HDd + 6 CoASH + 9 NADP + 5 ADP .
BIOMASSA : 205 G6P + 71 F6P + 897 Rb5P + 361 E4P + 129 G3P + 1496 PG3 + 519 PEP + 2833 PIR + 3748 AcCoA + 1079 KG2 + 1787 OAA + 3547 NAD + 18225 NADPH + 18485 ATP = 10000 XR + 18485 ADP + 3547 NADH + 18225 NADP + 3748 CoASH .
OXFAD : FADH2 + 2 ADP + O = FAD + 2 ATP .
OXNAD : NADH + 3 ADP + O = NAD + 3 ATP .
TRANS : NADH + ATP + NADP = NADPH + NAD + ADP .